RESEARCH
Overall, our research is focused on identifying ways to inhibit or prevent breast cancer progression.
LIPID METABOLISM IN CANCER PROGRESSION
Our laboratory is investigating the mechanism and function of abnormal lipid accumulation and metabolism in breast cancer, particularly in metastasis.
VITAMIN D INHIBITION OF CANCER
We are studying the impact of vitamin D on breast cancer from early to late progression, with a recent focus on regulation of cellular energy metabolism.
PYRUVATE CARBOXYLASE IN CANCER
In a collaborative study, we have previously demonstrated that the enzyme pyruvate carboxylase is essential for breast to lung metastasis. We are focused on the role of pyruvate carboxyalse in regulating energy metabolism, fatty acid synthesis and oxidative stress protection in stages of cancer progression.
DEVELOPING UNDERGRADUATE RESEARCH PROGRAMS
Dr. Teegarden is also engaged in developing effective programs to engage undergraduate students in research, and to enhance the experience to prepare them for future research careers. Programs include the Cancer Prevention Internship Program (CPIP, NIH funded), the Transdisciplinary Obesity Prevention Research program (TOPRs, USDA funded, https://stemedhub.org/groups/toprs/) and the college of Health and Human Sciences Research Education and Community Honors (REACH) Scholars program.
